ABSTRACT
Novel tetrahydroindeno[1,2-b]pyrrolidines were conveniently prepared in moderate to good yields via a sequential Ugi multicomponent reaction or Staudinger/aza-Wittig/Ugi combination, followed by the palladium-catalyzed aerobic oxidative cyclization of the resulting Ugi adducts.
GRAPHICAL ABSTRACT
![](/cms/asset/65ada309-1b52-4d95-bf3b-ba49c8978703/lsyc_a_1152372_uf0001_b.png)