ABSTRACT
A Cu(OTf)2-catalyzed simple synthetic approach for highly substituted 1-alkoxy imidazole has been described. This protocol involves (3 + 2) cycloaddition of oximino carbenoids with organo nitriles. This method has wide substrate scope and tolerates alkyl, aryl, substituted aryl, vinyl, and ester nitriles.
GRAPHICAL ABSTRACT
![](/cms/asset/6ca0ca13-0ece-4933-8f11-dfbf0da6722f/lsyc_a_1176200_uf0001_b.png)
Acknowledgment
The authors thank the administration and the management of Karunya University for their constant support and encouragement.