Evidence against the structure proposed for a natural phenylethanol isolated from mangrove Avicennia marina

ABSTRACT

In an effort to establish the absolute configuration of a previously reported natural triol, the proposed structure was synthesized in an enantiomerically enriched form. The synthetic sample showed NMR and specific rotation completely incompatible with those reported in the literature and thus disproved the previously assigned structure.

GRAPHICAL ABSTRACT

KEYWORDS:

• Configuration
• natural products
• structural determination
• triol

Acknowledgments

The research is supported by Jiangsu University (No. 14JDG018) and the Priority Academic Program Development of Jiangsu Higher Education Institutions.