ABSTRACT
Here we report a novel Baker yeast catalyzed one pot cyclocondensation, performed at room temperature in ethanol for obtaining high yields of polyfunctionalized pyridines, 2-amino-4-aryl-3,5-dicyano-6-phenylthiopyridines. The developed protocol obeys certain green principles and is scalable and cost effective.
GRAPHICAL ABSTRACT
![](/cms/asset/dadfbc0d-d867-4e98-9985-e495f70a14d4/lsyc_a_1350982_uf0001_oc.jpg)
Acknowledgments
The authors are thankful to Professor D. B. Ingle for his invaluable discussions and guidance. The authors are also thankful to SAIF, Central Drug Research Institute (CDRI), Lucknow for spectral analysis.