ABSTRACT
Mannich bases are formed in a noncatalytic multicomponent reaction, which is promoted by ultrasound irradiation. The procedure avoids the use of toxic solvents, catalyst, and purification, generating the desired compounds in excellent yields and short reaction times.
GRAPHICAL ABSTRACT
Acknowledgment
This work was supported by Council National of Science and Technology (SEP-CB-2011-01) under grant agreement No. 0167668. The author thanks BUAP for performed products characterization.