ABSTRACT
Molecular iodine has been used for the regioselective, one pot, direct synthesis of 3-iodoflavones from 2′-allyloxy chalcones, 2′-hydroxy chalcones and flavones. Allyl deprotection, cyclization dehydrogenation and α-iodination of 2′-allyloxychalcones has been achieved in a single step to offer 3-iodoflavones.
GRAPHICAL ABSTRACT
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Acknowledgment
Avinash M. Patil and Dayanand A. Kamble thank CSIR, New Delhi and UGC-DSK for the award of research fellowships.