Chromium(III) chelate of deoxyalliin and its bioactivity

Abstract

Chromium(III) chelate of deoxyalliin has been prepared and characterized using physical and spectral means and its bioactivity has been determined. FT-IR showed the coordination of amino and carboxylate groups of the amino acid to the metal. Elemental analysis, mass spectrometry, and TGA suggested its formula to be Cr(C₆H₁₀O₂NS)₃. UV-Vis spectroscopy and magnetic moment proved octahedral geometry. Conductivity measurement showed it to be a non-ionic compound. Bioactivity analysis showed that the complex is active against Gram-positive and Gram-negative bacteria and yeast as well.

Keywords:

• Chromium complex
• Deoxyalliin
• Antibiotic activity
• Organic chromium

Acknowledgments

The authors are highly grateful to Higher Education commission of Pakistan for funding this project and Mr Peter Wichta of University of Melbourne for helping in carrying out the analysis work.