Synthesis and evaluation of antioxidant and antibacterial properties of morin complexes

Abstract

This study examines the interaction of Mg(II) and Ca(II) with morin (2′,3,4′,5,7-pentahydroxyflavone) in conjunction with the appraisal of antioxidant and biological properties of the complexes. The complexes were characterized by UV-Vis spectroscopy, FT-IR, ¹H NMR, ¹³C NMR, thermal, and elemental analyses. The complexes have also been studied to determine metal : ligand stoichiometry. For antioxidant studies, it may be induced that complex formation increases the scavenging ability because of the differential and selective role of metals in free radical scavenging. The bioactivity studies show that both complexes have remarkable antibacterial properties against Micrococcus flavus and Staphylococcus aureus.

Keywords:

• Synthesis
• Properties
• Coordination
• Antimicrobial

Acknowledgments

This research work was supported by the National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro/Pakistan. The authors thank and gratefully acknowledge for this financial assistance and express their appreciations on the provision of necessary facilities.