Synthesis, crystal structure, and properties of cobalt, zinc, and manganese coordination polymers based on fluconazole

Abstract

Three complexes based on fluconazole, namely, {[Co₂(HFlu)(dpa)₂(H₂O)₂]·H₂O}_n (1), {[Zn(HFlu)(IPA)]·H₂O}_n (2), and {[Mn(HFlu)₂(IPA)(H₂O)]·H₂O}_n (3) (HFlu = fluconazole, 2-(2,4-difluoro-phenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol; H₂dpa = diphenic acid; H₂IPA = isophthalic acid) have been synthesized. Single-crystal X-ray analysis revealed that 1 is a 2-D-network framework containing a trinuclear Co(II) unit, 2 is a 3-D framework, and 3 is 1-D double chain structure with a Mn₂ metallocyclic core. The complexes have also been characterized by elemental analyses, IR, UV/vis and fluorescence spectroscopy, and thermal gravimetry. The phase purity of these polymers has been confirmed via powder X-ray diffraction.

Graphical Abstract

Keywords:

• Coordination polymer
• Fluconazole
• UV/vis spectra
• Fluorescence
• Thermal gravimetry

Funding

This work is supported by the Innovation Project of Guangxi University for Nationalities [grant number gxun-chx2013099]; the Natural Science Foundation of Guangxi [grant number 2012GXNSFAA053020]; and the National Natural Science Foundation of China [grant number 20761002], PR China.