Figures & data
Figure 1. NAC promotes the locomotor ability of rats with SCI after decompression surgery. BBB scores of rats in each group (0 represents no observable hind limb movements, 21 represents normal walking). Data presented as mean ± SD, n = 10.
Figure 2. NAC treatment for 2 months alleviates nerve damage in rats with SCI after decompression surgery. Histological analysis of injured spinal cords by LFB, NF-200, GFAP, and Nissl staining. Scale bar = 50 μm.
Figure 3. NAC attenuates inflammatory cell infiltration on the third day of treatment after decompression surgery in rats with SCI. Immunohistochemical analysis of F4/80 and detection of CD11b- and CD45-labeled cells. Data presented as mean ± SD, n = 3, *p < 0.05. Scale bar = 50 μm.
Figure 4. NAC attenuates inflammation in rats with SCI on the third day of treatment after decompression surgery. The expression of pro-inflammatory cytokines and chemokines in injured spinal cords. Data presented as mean ± SD, n = 5, *p < 0.05.
Figure 5. NAC attenuates apoptosis in rats with SCI treatment for 2 months after decompression surgery. (A) TUNEL staining and (B) protein expression of cleaved caspase-3 in injured spinal cords. Data presented as mean ± SD, n = 3, *p < 0.05. Scale bar = 50 μm.
