Evaluation of chronotype and sleep quality in infertile population and comparison with fertile population: a cross-sectional study

Figures & data

Figure 1. Flow chart of study population.

Table 1. Demographic characteristics of groups.

Characteristics	Infertile group (n = 110)	Fertile (control) group (n = 117)	p
Age (years), median (IQR)	32 (24 − 36)	32 (29–36)	NS
Gravida, median (IQR)	0 (0 − 1)	2 (1 − 2)	<0.001
Parity, median (IQR)	0 (0 − 0)	2 (1 − 2)	<0.001
BMI (kg/m^2), median (IQR)	25 (22 − 28)	24 (22 − 28)	NS
Infertility time (years), median (IQR)	4 (3 − 7)	–	–
Infertility type
Primary infertility, n (%)	75 (68.2%)	–	–
Secondary infertility, n (%)	35 (31.8%)	–	–
Smoking		–	NS
Smokers, n (%)	22 (20%)	26 (22.2%)	–
Nonsmokers, n (%)	88 (80%)	91 (77.8%)	–
Profession			NS
Housewife, n (%)	47 (42.7%)	45 (38.5%)	–
Officer, n (%)	61 (55.5%)	72 (61.5%)	–
Shift Worker, n (%)	2 (1.8%)	0 (0%)	–

NS: not significant; IQR: interquartile range.

p > 0.05.

Values are reported as median (IQR) and number (percentage).

Table 2. Comparison of MEQ and PSQI scores of groups.

Parameters	Infertile group (n = 110)	Fertile (control) group (n = 117)	p
MEQ group			<0.001
Morningness, n (%)	16 (14.5%)	46 (39.3%)^b	–
Intermediate, n (%)	68 (61.8%)	70 (59.8%)	–
Eveningness, n (%)	26 (23.6%)^a	1 (0.9%)	–
MEQ score, median (IQR)	50 (43 − 55)	56 (51–59)	<0.001
PSQI group			<0.001
<5, n (%)	30 (27.3%)	92 (78.6%)	–
>5, n (%)	80 (72.7%)	25 (21.45%)	–
PSQI score, median (IQR)	5 (4–6)	4 (3–4)	<0.001

NS: not significant; IQR: interquartile range.

p > 0.05.

Values are reported as median (IQR) and number (percentage).

^aIn post-hoc analysis, the main contribution for MEQ group differences was from eveningness chronotype group.

^bAfter exclusion of eveningness group difference of intermediate and morningness chronotypes was statistically important with Bonferroni correction (χ²(1, N = 200) = 9.67, p = 0.002). All group contributions for MEQ difference were statistically relevant.