Orbital osteomas associated with Gardner’s syndrome: a case presentation and review of literature

ABSTRACT

Gardner syndrome (GS) is a rare genetic disorder characterized by numerous intestinal colon polyps with various extraintestinal manifestations. Osteomas are a known extracolonic manifestation of GS and can affect the orbit, as seen in our patient, as well as 13 other cases documented in literature. Excision of large orbital osteomas can be successful with a multi-disciplinary approach as presented in this article. Ophthalmologists can even be the first to diagnose GS, usually via the presence of congenital hypertrophy of the retinal pigment epithelium (CHRPE) lesions. Untreated, 100% of colon polyps will transform into cancer, thus it is important to be aware of this rare syndrome with ophthalmic manifestations and screen patients with osteomas for GS.

KEYWORDS:

• Bony tumors
• familial adenomatous polyposis
• FAP
• Gardner’s syndrome
• orbital osteomas

Acknowledgements

The authors would like to thank the rhinology and skull base surgeons at Emory University Hospital.

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/01676830.2022.2080231

Additional information

Funding

The author(s) reported that there is no funding associated with the work featured in this article.