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Journal of Dispersion Science and Technology Volume 31, 2010 - Issue 11
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Original Articles

The Effect of Oil Components and Homogenization Conditions on the Physicochemical Properties of Zedoary Turmeric Oil Submicron Emulsions

Peng-Fei Yue Jiangxi University of Traditional Chinese Medicine, Nanchang, P. R. China; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Nanchang, P. R. ChinaCorrespondence[email protected]
,
Xiu-Yun Lu College of Pharmacy, Gannan Medical University, Ganzhou, P. R. China
,
Mei-Xiang Liao College of Pharmacy, Gannan Medical University, Ganzhou, P. R. China
,
Hai-Long Yuan 302 Hospital of PLA&PLA Institute of Chinese Materia Medica, Beijing, P. R. China
,
Wei-Feng Zhu Jiangxi University of Traditional Chinese Medicine, Nanchang, P. R. China; College of Pharmacy, Jiangxi University of TCM, Nanchang, P. R. China
&
Ming Yang Key Laboratory of Modern Preparation of TCM, Ministry of Education, Nanchang, P. R. China
Pages 1535-1540 | Received 08 Jun 2009, Accepted 14 Jul 2009, Published online: 05 Nov 2010
 
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Abstract

Zedoary turmeric oil submicron emulsions were studied. The effects of the oil phase as a mixture (ternary) on the emulsion droplet size were investigated by means of the simplex lattice design. By optimizing the homogenization process and using only 1.2% soya lecithin, emulsions with 20% oil phase consisting of zedoary turmeric oil–MCT–soybean oil ratio of 0.5:0.25:0.25 with particle sizes in the range of 132–148 nm and moderate viscosity (3.6–4.0 mPa · s) could be prepared. These emulsions showed good stability over 6 months. This study showed the dominating influence of composition of the oil phase as well as the importance of the homogenizing conditions on processing and stability of the zedoary turmeric oil submicron emulsions.

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