http://orcid.org/0000-0003-3842-8881
Figures & data
Figure 1. A schematic overview of miRNA and lncRNA interplay between host and viral genome ncRNAs.
Figure 2. An overview of gene expression regulation by the SINE B2 RNA. Recruitment of the protein EZH2 during cellular response to stress leads to B2 RNA cleavage and release of RNA Pol II transcription of IEGs. IEG: Immediate Early Genes.
Table 1. Advantages and disadvantages of various sequencing technologies. Advantages and disadvantages are related to the sequencing chemistry behind each platform that influences approximate read lengths afforded by each technology as well as the error rate in base calling for the sequenced reads.
Table 2. Examples of size-specific RNAseq. Varying read lengths can be used for a variety of purposes. Long RNAseq can be used for differential expression, detection of viral integration and diagnosis of influenza. Short RNAseq can be used to observe processing events, and small RNAseq can be used to quantify differential expression of miRNAs. nt: nucleotides.
Figure 3. Common RNA genomics applications in virology. Genomic DNA is transcribed into RNA precursors for protein production (2–3%) and non-coding transcripts (74–90%). Abundance, identity and interaction data for RNA transcripts of varying lengths can be obtained with RNA genomic techniques.
