Figures & data
Figure 1. Image of the VX2 carcinoma on a donor rabbit.
Figure 2. The cavity created for accommodating the CITT probe prior to placement of the device (A), after placing the CITT device (B) and at the end of the CITT ablation (C).
Figure 3. A carcinoma mass developed after partial resection of the primary tumour in control group.
Figure 4. The ablation site at 10 weeks post-CITT treatment showing no signs of scarring. The skin (A) and muscle (B) healed.
Figure 5. H&E staining of histological slides that were taken from tissue collected at the ablation site at 10 weeks post CITT treatment. Complete dermal healing (A). Dense mature fibrous tissue (arrow) is present in healed dermis. Adjacent dermis (star) is normal. Residual inflammation was present in 10/12 animals (B, C, D). (B) Cellular debris and inflammatory cells (star) are walled off by a capsule of fibrous connective tissue (arrow). (C) Fragments of skeletal myofibres (arrow) are surrounded by necrotic cellular debris and inflammatory cells. (D) Inflammatory infiltrate surrounding myofibre. H&E, magnification 20× (A), 40× (B), 200× (C) and 400× (D).
