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Research Article

The effect of time interval between radiotherapy and hyperthermia on planned equivalent radiation dose

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & show all
Pages 901-909 | Received 14 Oct 2017, Accepted 20 Apr 2018, Published online: 11 May 2018

Figures & data

Figure 1. Workflow for equivalent radiation dose calculation of a combined treatment with radiotherapy (RT) and hyperthermia (HT). Reproduced from Crezee et al. [Citation23] with permission.

Figure 1. Workflow for equivalent radiation dose calculation of a combined treatment with radiotherapy (RT) and hyperthermia (HT). Reproduced from Crezee et al. [Citation23] with permission.

Figure 2. Temperature-volume indices for each of the structures of interest, as calculated from the hyperthermia treatment plans of 15 patients.

Figure 2. Temperature-volume indices for each of the structures of interest, as calculated from the hyperthermia treatment plans of 15 patients.

Figure 3. DVH indices for each of the structures of interest, as calculated from the radiation treatment plans of 15 patients.

Figure 3. DVH indices for each of the structures of interest, as calculated from the radiation treatment plans of 15 patients.

Figure 4. The ratios (TER(D98%) and TER(Dmean)) and difference (ΔV45Gy) between the thermoradiotherapy treatment plans and corresponding radiation-only treatment plans of 15 patients, as a function of the time interval between radiation and hyperthermia treatment. Similar figures for the ΔV30Gy and D2cm3 (organs at risk) and the D2% and EUD (GTV) can be found in Supplementary Figure A1.

Figure 4. The ratios (TER(D98%) and TER(Dmean)) and difference (ΔV45Gy) between the thermoradiotherapy treatment plans and corresponding radiation-only treatment plans of 15 patients, as a function of the time interval between radiation and hyperthermia treatment. Similar figures for the ΔV30Gy and D2cm3 (organs at risk) and the D2% and EUD (GTV) can be found in Supplementary Figure A1.

Figure 5. Therapeutic gain factors for thermoradiotherapy compared to radiation alone of 15 patients, as a function of the time interval between radiation and hyperthermia treatment.

Figure 5. Therapeutic gain factors for thermoradiotherapy compared to radiation alone of 15 patients, as a function of the time interval between radiation and hyperthermia treatment.
Supplemental material

IHYT_1468930Supplemental_File.pdf

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