US-guided microwave ablation for secondary hyperparathyroidism in patients after renal transplantation: a pilot study

Figures & data

Table 1. Baseline clinical characteristics of RT patients with SHPT treated with MWA.

No.	Age/sex	Time of after RT (months)	Size (cm)	Location	Ablation time(s)	Follow-up (months)	No. of puncture sites per nodule
1	40/M	22	1.3 × 0.6	L	180	18	6
			1.3 × 0.8	L	300		6
			0.4 × 0.4	R	120		1
2	63/F	6	1.6 × 1.2	R	360	15	7
			1.2 × 0.9	R	250		6
3	39/M	32	1.3 × 1.1	L	240	16	6
4	38/M	19	1.3 × 0.9	R	250	20	6
5	53/M	26	1.2 × 0.6	L	270	19	6
6	56/F	79	1.5 × 1.2	R	360	17	7
			1.2 × 0.9	R	300		5
7	62/M	114	1.4 × 1.1	R	360	15	7
8	48/M	43	1.8 × 0.9	R	435	17	8
9	48/F	66	2.0 × 0.7	L	360	18	9
			1.3 × 0.8	L	240		5

L: left; R: right.

Table 2. Laboratory data of RT patients with SHPT before or after MWA.

Parameters	Before MWA	After MWA (1 day)	After MWA (1 month)	End of Follow-up
Intact PTH (pg/mL)^a	780.0	69.6*	134.0*‡	134.0*‡§
Calcium (mmol/L)^b	2.62 ± 0.32	2.23 ± 0.29*	2.21 ± 0.40*‡	2.27 ± 0.13*‡§
Phosphorus (mmol/L)^b	1.39 ± 0.61	1.22 ± 0.48	1.47 ± 0.60	1.17 ± 0.43
Blood creatinine (umole/L)^b	88.9 ± 26.7	98.6 ± 19.2	97.6 ± 12.3	94.5 ± 14.7
Blood urea nitrogen (mmol/L)^b	5.7 ± 1.6	5.6 ± 1.6	6.6 ± 1.2	6.7 ± 1.4

^aThe levels of intact PTH were expressed by median.

^bThe levels of calcium, phosphorus, creatinine and urea nitrogen were expressed by mean ± SD.

*p < .01 versus before MWA.

‡p < .01 versus after MWA (1 day).

§p < .01 versus after MWA (1 month).

Figure 1. MWA of SHPT nodule in a patient who had undergone successfully renal transplantation. (A) The nonuniform hypoechoic nodule (Arrow) was disclosed by preablation ultrasound in neck. (B1) The CT scan showed there is a small nodule (Arrow) locating in the right front of trache, which corresponds to the one in ultrasound; (B2) The nodule has radioactivity concentration (Arrow) in late phase of MIBI scan. (C) An uniform hyperenhancement of nodule (Arrow) was displayed in CEUS preablation. (D) The spacer fluid was injected surrounding the nodule, which displayed non echo area (Arrow). (E)The hyperechoic emerging inside nodule (Arrow) during ablation. (F) A non-enhancement area covered the nodule (Arrow) after ablation, which suggested a complete ablation.