Mid-term results of MR-guided high-intensity focused ultrasound treatment for relapsing superficial desmoids

Figures & data

Figure 1. (a) MRI (T1 FS SPIR sequence with contrast) of popliteal fossa before treatment. (b) Subtraction sequence with contrast directly post-HIFU. (c) Post-processing of lesion with tumor tracking tool. Note that due to (unfortunate) different angulation of MR-sequences pre- and post-contrast the bone is not in the same plane as the tumor in the pre-contrast sequence.

Table 1. Summary of patient data incl. prior treatments, effect of HIFU, and adverse effects.

Patient no.	Age at tumor onset	Tumor location	Prior treatment	Type of anesthesia	No. of HIFU treatments	Months of follow-up	Initial tumor volume (ml)	Most recent tumor volume (ml)	Change in tumor volume (ml)	Shortest distance to skin (cm)	Adverse events
1	40	Popliteal fossa	Surgery (4×)	Regional (sciatic and femoral nerve) and spinal	2	13	70	19	−73%	0.6	1st degree burn
2	40	Intercostal muscles	Surgery (1×)	Local	1	20	3	0	−100%	1.5	2nd degree burn
3	42	Rectus abdominis muscle	Surgery (1×)	Oral pain medication	1	27	3	0	−100%	2.5	None
4	79	Deltoid muscle	Surgery (1×)	Regional	2	15	22	6	−73%	0.9	1st degree burn
5	44	Rectus abdominis muscle	Surgery (1×), Radiation (1×)	Regional (brachial plexus) and epidural	3	60	23	0	−100%	0.5	2nd degree burn

Figure 2. MRI (T1 FS SPIR sequence with contrast) of lower abdomen with desmoid within the left lower rectus abdominis muscle: (a) before treatment and (b) five years after treatment with no residual tumor.