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Review Article

Analysis of the results of high-intensity focused ultrasound for patients with advanced pancreatic cancer

, & ORCID Icon
Article: 2250586 | Received 25 May 2023, Accepted 16 Aug 2023, Published online: 28 Aug 2023

Figures & data

Table 1. Patient characteristics and therapeutic parameters.

Figure 1. Efficacy of HIFU ablation. (1) Pretreatment ultrasound images. (2) Post-treatment ultrasound image showing overall grey scale changes in the target area. (1) and (2) are taken from the same patient. (3) Pretreatment CT presentation of pancreatic body caudal tumor. (4) Follow-up enhanced MRI after 1 month of treatment, with no enhancement in the area of the lesion (indicated by the arrow) and significant coagulative necrosis of the lesion seen in delayed phase. (3) and (4) are taken from the same patient.

Figure 1. Efficacy of HIFU ablation. (1) Pretreatment ultrasound images. (2) Post-treatment ultrasound image showing overall grey scale changes in the target area. (1) and (2) are taken from the same patient. (3) Pretreatment CT presentation of pancreatic body caudal tumor. (4) Follow-up enhanced MRI after 1 month of treatment, with no enhancement in the area of the lesion (indicated by the arrow) and significant coagulative necrosis of the lesion seen in delayed phase. (3) and (4) are taken from the same patient.

Figure 2. VAS score curve.

Figure 2. VAS score curve.

Table 2. SIR classification of complications of patients treated with HIFU.

Figure 3. Results of single-factor analysis affecting OS. (a) Effect of local response rate on OS: Patients with complete response (CR) and partial response (PR) had a significantly better prognosis than those with stable disease (SD) and progressive disease (PD). (b) Effect of combination chemotherapy on OS. (c) Effect of tumor staging on OS.

Figure 3. Results of single-factor analysis affecting OS. (a) Effect of local response rate on OS: Patients with complete response (CR) and partial response (PR) had a significantly better prognosis than those with stable disease (SD) and progressive disease (PD). (b) Effect of combination chemotherapy on OS. (c) Effect of tumor staging on OS.

Table 3. Log-rank one-way analysis of factors affecting OS.

Table 4. Multi-factor analysis of Cox affecting OS.