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Research Article

Efficacy and pregnancy outcomes of focused ultrasound for cervical high-grade squamous intraepithelial lesions

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Article: 2250936 | Received 30 May 2023, Accepted 17 Aug 2023, Published online: 04 Sep 2023

Figures & data

Figure 1. Study flow chart. FU: focused ultrasound; HSIL: High-grade intraepithelial lesions; HR-HPV: high-risk human papillomavirus.

Figure 1. Study flow chart. FU: focused ultrasound; HSIL: High-grade intraepithelial lesions; HR-HPV: high-risk human papillomavirus.

Table 1. Baseline demographics and edical history.

Table 2. Adverse effects of FU treatment.

Figure 2. Colposcopy images of CIN2 before FU treatment (A/B/C) and at 6 months after FU treatment (D/E/F). (A) the cervix was exposed and the squamocolumnar junction was fully visible. (B) With a 5% acetic acid test, thin acetowhite soon appeared in the transformation area, and the edge thickened, especially in the direction of 12 o‘clock, as indicated by the arrow. (C) With a 1% iodine test, the transformation area and local edges were unstained, especially at the point indicated by the arrow. (D) The cervix was completely covered with mature squamous epithelium. (E) With a 5% acetic acid test, an obvious abnormality was not observed. (F) With a 1% iodine test, the entire cervical surface was stained.

Figure 2. Colposcopy images of CIN2 before FU treatment (A/B/C) and at 6 months after FU treatment (D/E/F). (A) the cervix was exposed and the squamocolumnar junction was fully visible. (B) With a 5% acetic acid test, thin acetowhite soon appeared in the transformation area, and the edge thickened, especially in the direction of 12 o‘clock, as indicated by the arrow. (C) With a 1% iodine test, the transformation area and local edges were unstained, especially at the point indicated by the arrow. (D) The cervix was completely covered with mature squamous epithelium. (E) With a 5% acetic acid test, an obvious abnormality was not observed. (F) With a 1% iodine test, the entire cervical surface was stained.

Table 3. HSIL outcomes after FU treatment.

Table 4. HR-HPV clearance rate after FU treatment.

Table 5. Fertility and pregnancy outcomes after FU.

Date availability statement

Relevant data about this study are available from the corresponding author upon reasonable request.