Percutaneous microwave ablation on management of hereditary renal cell carcinoma in Von Hippel–Lindau disease

Figures & data

Figure 1. Research flowchart. RCC: renal cell carcinoma; MWA: microwave ablation; VHL: Von Hippel-Lindau disease.

Table 1. General information of patients (n = 10) and tumors (n = 28) included.

Variable	Result
Age at surgery, yr
Mean (range)	39.5 (20–57)
Male/female, n(%)	3(30)/7(70)
Tumor dia, cm
Mean (range)	3.0 (1.7–7.1)
Tumor vol. per session, ml
Mean (range)	20.7 (1.9–174.3)
CCI, n(%)
2	5(50)
3	4(40)
≥4	1(10)
Single kidney, n(%)
No	7(70)
Yes	3(30)
BMI, kg/m^2
Mean (range)	23.8 (18.7–26.3)
R.E.N.A.L score, n(%)
Low complexity	10(35.7)
Intermediate complexity	14(50.0)
High complexity	4 (14.3)
Histology, n(%)
Clear cell	28(100)
eGRF, n(%)
<90 ml/(min*1.73m^2)	3(30)
>90 ml/(min*1.73m^2)	7(70)
Intraprocedure time, h
Mean(range)	1.3(0.8–2.0)
Follow-up time, mon
Median(range)	52(8-97)

CCI: Charlson Comorbidity Index; BMI: Body Mass Index;.

eGFR: estimated Glomerular Filtration Rate.

Table 2. Renal functions and complications outcomes before and after microwave ablation.

	Pre-ablation	Post-ablation	р value
Creatinine, µmol/L mean (range)	102.0 (47.6-161.0)	112.3 (47.6-196.0)	0.06
eGFR, mL/(min*1.73m2) Mean (range)	78.0 (43.0-153.5)	72.1 (34.0-153.5)	0.04
Major complications, n(%)	0 (0)	0 (0)

Figure 2. Kaplan–Meier survival analysis.

Availability of data and materials

The datasets analyzed in this manuscript are not publicly available. Requests to access the datasets should be directed to [email protected]