Network-based topic structure visualization

Figures & data

Figure 1. If topics are located in the center in latent position (a), two distinct subgroups are observed in the score and affinity plot (b). Otherwise, such subgroup patterns are not observed in the score and affinity plot (c). In (b) and (c), the orange color (id of 1) indicates the top 20% of words of high score words while the green color (id of 0) indicates the remaining words. (a) Topics' latent positions of ${\mathbf{B}}_{47\mathrm{\%}}$. (b) The score and affinity plot of Topic 19 in ${\mathbf{B}}_{47\mathrm{\%}}$ and (c) The score and affinity plot of Topic 3 in ${\mathbf{B}}_{47\mathrm{\%}}$.

Table 1. Interpretation of the topic based on ${\mathbf{A}}_{47\mathrm{\%}}^{\ast }$ matrix.

Topic	Name	Top score words
1	Lung Scan (Imaging)	subpleural	crazy paving	bronchogram
		(0.963)	(0.957)	(0.950)
2	Compound and Drug	Protein Data Bank	papain-like	intermolecular
		(0.938)	(0.936)	(0.934)
3	Microbiome	${\mathrm{DHA}}^{\ast }$	biofilm	vancomycin-resistant
		(0.968)	(0.968)	(0.967)
4	Treatment of Other Diseases	sarcoma	arthroplasty	neoadjuvant
		(0.948)	(0.944)	(0.943)
5	Cardiovascular (Symptom)	vein	antithrombotic	${\mathrm{VTE}}^{\ast }$
		(0.906)	(0.899)	(0.898)
6	Molecular-level Response to Infection	${\mathrm{NLRP}3}^{\ast }$	metalloproteinase	upregulation
		(0.929)	(0.927)	(0.926)
7	COVID-19 Risk Prediction Markers	alanin	${\mathrm{BUN}}^{\ast }$	prealbumin
		(0.976)	(0.972)	(0.969)
8	Literature Review	Prospero DB	Wanfang DB	meta-analys
		(0.967)	(0.966)	(0.944)
9	Symptom and Comorbidity	petechiae	guillain-barre syndrome	ageusia
		(0.958)	(0.955)	(0.952)
10	Cardiovascular	infarction	thromboprophylaxis	${\mathrm{VTE}}^{\ast }$
		(0.912)	(0.909)	(0.909)
11	Social Impact	classroom	pedagogy	zoom
		(0.925)	(0.911)	(0.906)
12	Financial and Economical Impact	macroeconomics	monetary	profit
		(0.929)	(0.928)	(0.928)
13	Statistical Modeling	Weibull	least-square	${\mathrm{MAE}}^{\ast }$
		(0.984)	(0.975)	(0.966)
14	COVID-19 Test	${\mathrm{LFIAs}}^{\ast }$	transcription-${\mathrm{PCR}}^{\ast }$	Wantai
		(0.979)	(0.974)	(0.972)
15	Mental Issues	anxious	${\mathrm{PTSD}}^{\ast }$	post-traumatic
		(0.942)	(0.940)	(0.935)
16	Lung Scan	procalcitonin	ground-glass	opacity
		(0.924)	(0.922)	(0.916)
17	Treatment of COVID-19	reintubation	multi-centric	Hydroxychloroquine
		(0.943)	(0.943)	(0.937)
18	Respiration	laryngoscope	facepiece	supraglottic
		(0.978)	(0.978)	(0.975)
19	Prevention of COVID-19	alcohol-based	decontamination	rub
		(0.944)	(0.941)	(0.919)
20	Immunology and Virus	${\mathrm{MHC}}^{\ast }$	multi-epitope	immunodominant
		(0.976)	(0.975)	(0.973)

Note: The abbreviation is marked by an asterisk and a more detailed interpretation can be found in the Supplemental Materials (see Appendix H).

Figure 2. Topic architecture visualization of COVID-19 literature with three topic clusters (A)–(C). The arrow indicates the direction of latent positions by increasing the word size. (A) COVID-19 and its impacts on different areas. (B) Symptoms and treatment of COVID-19 and relevant studies. (C) Molecular studies associated with the COVID-19 infection.