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Original Articles

Severity of Pain and Sleep Problems during Kratom (Mitragyna speciosa Korth.) Cessation among Regular Kratom Users

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Pages 266-274 | Received 14 Nov 2017, Accepted 02 Jan 2018, Published online: 20 Mar 2018
 

ABSTRACT

Kratom (Mitragyna speciosa Korth.) is traditionally used in Southeast Asia for its medicinal value and psychoactive properties. Nonetheless, cessation from regular kratom use is reported to cause unpleasant dose-dependent withdrawal symptoms. This study aims to evaluate the severity of pain and sleep problems following the cessation of kratom tea/juice consumption among regular kratom users. A total of 170 regular users were recruited through snowball sampling for this cross-sectional study. The Brief Pain Inventory (BPI) and Pittsburgh Sleep Quality Index (PSQI) scales were administered to assess the severity of pain and sleep problems. Most participants experienced moderate pain intensity (84%) and moderate pain interference (70%) during kratom cessation; 46% experienced more sleep problems during kratom cessation. Individuals who consumed ≥4 glasses of kratom tea/juice (about 76–115 mg of mitragynine) daily had higher odds of reporting some pain interference (OR: 2.0; CI: 1.04–3.93: < .028), and sleep problems during kratom cessation (OR: 2.0; CI: 1.08–3.68: < .020), as compared to those who consumed 1–3 glasses of kratom tea/juice daily. However, the effects were still relatively mild. Cessation from regular kratom tea/juice consumption is not associated with prolonged pain and sleep problems, as compared to those reported for opioid analgesics.

Acknowledgments

The authors thank Mr. Azlan Abdul Rahim, Mr. Mohd Hafifi Jamri, and Mr. Muhammad Eshal Bin Dzulkapli for their kind assistance in data collection, and Mrs. Nur Sabrina Mohd Yusof for conducting the laboratory analysis to determine the mitragynine content in the acquired kratom juice samples.

Additional information

Funding

This work was supported by the Universiti Sains Malaysia through a Research Universiti grant (101/CDADAH/816306).

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