Functioning thyroid carcinomas-some historical aspects

Figures & data

Figure 1.  A 58 year old woman with metastatic thyroid cancer. Euthyroid (left panel), hyperthyroid due to functioning mediastinal metastases (middle panel), and euthyroid after thyroidectomy and ¹³¹I treatment and on thyroid hormone substitution (right panel).

Figure 2.  Profile scanning of ¹³¹I uptake showing initial uptake over metastases in the mediastinum. After ¹³¹I treatment uptake in the thyroid rest is observed. After retreatment with ¹³¹I also the thyroid rest is ablated.

Figure 3.  A 67 year old woman with thyroid cancer and a skeletal metastasis in the forehead.

Figure 4.  Scanning of ¹³¹I uptake showing the accumulation in the thyroid and the metastasis.

Figure 5.  The patient in Figure 3, 19 months after thyroidectomy, ¹³¹I treatment, external radiotherapy and thyroid hormone substitution.

Figure 6.  Scanning of ¹³¹I uptake in a 42 year old woman with thyroid cancer operated with right-sided hemithyroidectomy (left panel). The right panel shows uptake in lymph node metastases on the right side of the neck and in the mediastinum following ¹³¹I treatment.

Figure 7.  Profile scanning of the same patient as in Figure 6.

Figure 8.  Whole body scanning of ¹³¹I uptake in a 52 year old man with metastatic thyroid cancer. Metastases to the liver, the lungs and the skeleton are demonstrated.

Figure 9.  Liver metastasis of thyroid cancer (compare scan in Figure 8).

Figure 10.  Demonstration of the epilation caused by ¹³¹I treatment of a metastasis in the skull (left panel). The right panel shows later regrowth of hair.

Figure 11.  Chest radiography showing two pulmonary metastases in a 38 year old woman with thyroid cancer.

Figure 12.  The same patient as in Figure 11 after hypophysectomy demonstrating regression of the metastases.

Figure 13.  Diagram showing the initial very slow progression of two pulmonary metastases and then the effect of hypophysectomy (compare Figure 12 & Figure 13).