EBV positivity in primary cutaneous large B-cell lymphoma with immunophenotypic features of leg type: An isolated incidence or something more significant?

Figures & data

Figure 1.  H and E stained section showing the neoplastic lymphoid infiltrate composed of large cells with vesicular chromatin and single to several nucleoli resembling centroblasts and immunoblasts. Scattered apoptotic bodies, mitotic figures and pleomorphic cells are noted (original magnification×400).

Figure 2.  CD20 immunostain demonstrates the neoplastic infiltrate to be B-cells (original magnification×400).

Figure 3.  The neoplastic large B-cells are Bcl2 protein positive (original magnification×200).

Figure 4.  EBV in situ hybridization demonstrates positivity in the neoplastic large B-cells (original magnification×400).