Figures & data
Figure 1. Levels of stromal (top) and epithelial (bottom) GABAar immunostaining in 148 human prostate cancer specimens.
Figure 2. GABAa receptor (GABAar) immunostaining in human prostate specimens. Representative prostate cancer specimens showing low (A), moderate (B) and high (C, D) stromal immunostaining. GABAar immunoreactivity in the stroma of one normal (E) and one BPH (F) specimen. GABAar immunostaining in the acinar epithelium of a prostate cancer specimen (G). Magnification 100×(A-F) and 400×(G, H). A magnified region (400×) within D is shown in H.
Figure 3. Western blot of cell extracts from 4 human prostate cancer cell lines (LNCaP, MDA-PCA-2B, PC3 and DU145) and 3 human colon carcinoma cell lines (SW116, LoVo and LS174t), using anti-GABAa receptor (α-6 subunit) antibody.
Figure 4. Effect of isoguvacine (top) and dihydroergotoxine (bottom) on the proliferation of four human prostate cancer cell lines.
