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Original Article

Proteomic analysis of protein expression in human tonsillar cancer differentially expressed proteins characterize human tonsillar cancer

, , , , , , , , , , & show all
Pages 1493-1501 | Received 27 Nov 2007, Published online: 08 Jul 2009

Figures & data

Table I.  Biographic data and tumor classification.

Figure 1.  Mastergel with identified protein spots and the corresponding histograms (average protein expression and standard deviation)

Figure 1.  Mastergel with identified protein spots and the corresponding histograms (average protein expression and standard deviation)

Figure 2.  (a) Two representative 2-DE gels, pH 4-7 of a normal and a tumor sample. Close-up areas showing the Rho-GDI protein spot (arrow). (b). Representative PDQuest screenshot showing six segments of “normal gels” and five of “tumor gels”. The Rho-GDI spot is marked with a yellow square throughout all members. The master gel shows the corresponding histograms with the tumor sample marked in green and the normal sample marked in red. (c). Multi-channel view of the same gel-segments (Rho-GDI) visualizing the overexpressed protein in the tumor sample (blue) and the normal control (red). (d). 3-D rendered close-up segments confirming the Rho-GDI over expression in the tumor samples (arrows).

Figure 2.  (a) Two representative 2-DE gels, pH 4-7 of a normal and a tumor sample. Close-up areas showing the Rho-GDI protein spot (arrow). (b). Representative PDQuest screenshot showing six segments of “normal gels” and five of “tumor gels”. The Rho-GDI spot is marked with a yellow square throughout all members. The master gel shows the corresponding histograms with the tumor sample marked in green and the normal sample marked in red. (c). Multi-channel view of the same gel-segments (Rho-GDI) visualizing the overexpressed protein in the tumor sample (blue) and the normal control (red). (d). 3-D rendered close-up segments confirming the Rho-GDI over expression in the tumor samples (arrows).

Table II.  Identified proteins using MALDI-TOF and Swiss Prot/ Expasy database.

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