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ORIGINAL ARTICLES: Haematological malignancies

Sporadic occurrence of non-diagnosed IgG4-related disease in lymphoma patients with a previous Sjögren’s syndrome diagnosis

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Pages 1139-1144 | Received 13 Jan 2016, Accepted 19 Apr 2016, Published online: 19 May 2016

Figures & data

Figure 1. Unspecified low-grade B-cell lymphoma with features of IgG4-related disease in the resected submandibular gland. (a) Abundant infiltration by small lymphocytic and plasma cells, and features of storiform fibrosis (hematoxylin and eosin staining, magnification ×100). (b) IgG4+ plasma cells located in the periphery of the lymphoma tissue (magnification ×400). (c) IgG + plasma cells (magnification ×400). (d) CD138+ plasma cells (magnification ×400).

Figure 1. Unspecified low-grade B-cell lymphoma with features of IgG4-related disease in the resected submandibular gland. (a) Abundant infiltration by small lymphocytic and plasma cells, and features of storiform fibrosis (hematoxylin and eosin staining, magnification ×100). (b) IgG4+ plasma cells located in the periphery of the lymphoma tissue (magnification ×400). (c) IgG + plasma cells (magnification ×400). (d) CD138+ plasma cells (magnification ×400).

Figure 2. The lung tissue biopsied before lymphoma diagnosis shows dense lymphoplasmacytic infiltration rich in IgG4 + plasma cells, germinal center, and storiform fibrosis (magnification ×100).

Figure 2. The lung tissue biopsied before lymphoma diagnosis shows dense lymphoplasmacytic infiltration rich in IgG4 + plasma cells, germinal center, and storiform fibrosis (magnification ×100).

Table 1. IgG4 + plasma cells in the lymphoma tissue of 79 patients with an initial primary Sjögren’s syndrome diagnosis.

Supplemental material

Vasaitis_Supplementary_Table_I.docx

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