Volumetric response of intracranial meningioma after photon or particle irradiation

Figures & data

Table 1. Patients' characteristics.

	Proton	IMRT + C^12 boost	IMRT	FSRT
Patients (n)	27	11	16	23
Gender m:f (n)	4:23	5:6	5:11	6:17
WHO Grade (n)
Unknown	10	–	4	8
I	17	–	7	9
II	–	10	3	4
III	–	1	2	2
Localization (n)
Skull base	23	8	13	12
Olfactory tract	3	1
Falx cerebri	–	2	–	2
Orbita	–	1
Convexity	–	–	2	3
Cavernous sinus	–	–	–	4
N. opticus	–	–	–	2
Craniocervical junction	–	–	1	–
Cause of RT (n)
Inoperable	10	0	4	8
Residual	3	3	3	7
Recurrent	14	8	9	8
In. Vmean (cm^3)	26.1 ± 22.2	26.5 ± 15.4	37.3 ± 29.5	26.7 ± 23.1
1y Vmean (cm^3)	23.5 ± 19.8	20.9 ± 14.4	34.6 ± 28.0	20.5 ± 14.3
Rel. TV at 1y (%)	86.4 ± 15.6	77.9 ± 22.0	89.2 ± 24.9	84.0 ± 22.9
2ys Vmean (cm^3)	24.3 ± 20.7	12.9 ± 10.0	23.5 ± 17.5	13.9 ± 10.0
Rel. TV at 2y (%)	86.2 ± 9.2	70.1 ± 23.5	69.4 ± 17.7	77.0 ± 14.6

Figure 1. Treatment plans of three patients: IMRT (A), protons (B), and carbon ion boost according to MARCIE protocol (C).

Figure 2. Absolute TV changes according to RT modalities.

Figure 3. (0) Baseline MRI (for treatment planning) and follow-up MRIs after one (1) and two years (2) after RT by photons (A), protons (B) and after a combined RT by photons and carbon ions according to the MARCIE-protocol (C).

Figure 4. Relative TV changes according to gender.

Figure 5. Relative TV changes according to WHO grade.