Early death in Danish stage I lung cancer patients: a population-based case study

Figures & data

Table 1. Descriptive characteristics at time of diagnosis according to treatment modality for the patients who died within 1 year and the full population of stage I lung cancer patients diagnosed in Denmark, 2011–2014 (DLCR cohort).

	Death within 1 year				DLCR cohort, n = 2966	p-Value
	Total, n = 221	Surgery, n = 127 (57%)	Oncology, n = 86 (39%)	Palliative, n = 8 (4%)
Age mean (range) (years)	73.1 (45–89)	71.7 (45–86)	74.5 (53–89)	80.0 (72–86)	69.3 (17–96)	<.001
Gender female/male (%)	43/57	37/63	55/45	25/75	55/45	.004
TNM
T1aN0M0 – stage IA (%)	34	34	37	13	40	.134
T1bN0M0 – stage IA (%)	25	20	31	38	25	.837
T2aN0M0 – stage IB (%)	40	46	31	50	36	.180
Histology	n = 219				n = 2841
Adenocarcinoma (%)	44	41	49	38	52	.026
Squamous-cell carcinoma (%)	31	32	29	25	23	.013
Non-small-cell carcinoma (%)	16	17	14	38	14	.417
Small-cell carcinoma (%)	3	2	5	0	2	.142
Adenosquamous (%)	1	2	0	0	1	.873
Carcinoid (%)	1	2	0	0	4	.013
Large-cell neuroendocrine (%)	2	3	0	0	1	.187
Not otherwise specified (NOS) (%)	2	1	4	0	1	.629
Mixed type (%)	<1	1	0	0	<1	.887
Charlson comorbidity index (mean)	2.3	1.9	2.7	2.3	N/A	N/A

Null hypotheses were tested between the total group of cases and the DLCR cohort. TNM classifications are according to the 7th edition. N/A, not available.

Figure 1. Distribution of primary causes of death among 213 curatively treated stage I lung cancer patients diagnosed from 2011 to 2014.

Table 2. The cause of death by type of curative treatment among stage I lung cancer patients, diagnosed 2011–2014, who died within a year of diagnosis.

Type of surgery	Number of cases	Lung cancer	Treatment complications	Co-morbidity	Others	Unknown
Explorative	2 (1)	1	1	0	0	0
Segmental resection	1	0	1	0	0	0
Wegde resection	36 (1)	12	6	11	2	5
Lobectomy	78 (4)	21	27	10	4	16
Bilobectomy	5	1	3	1	0	0
Pneumectomy	5 (1)	3	0	1	1	0
Subtotal	127 (7)	38	38	23	7	21
Oncological treatment
SBRT	78 (8)	20	2	24	3	29
Chemo/radiotherapy	8 (1)	4	0	3	0	1
Subtotal	86 (9)	24	2	27	3	30
Total	213 (16)	62	40	50	10	51

SBRT: stereotactic body radiotherapy. Numbers in parentheses state the number of patients treated but had residual disease at the end of treatment or who did not complete treatment.