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ORIGINAL ARTICLE: MEDICAL ONCOLOGY

Anti-androgen monotherapy versus gonadotropin-releasing hormone agonists in men with advanced, non-metastatic prostate cancer: a register-based, observational study

, , ORCID Icon, , , & show all
Pages 110-118 | Received 27 Feb 2018, Accepted 20 Sep 2018, Published online: 30 Oct 2018

Figures & data

Figure 1. CONSORT diagram.

Figure 1. CONSORT diagram.

Figure 2. First event of conversion from AA to GnRH agonist, death from other causes or death from PCa assessed in competing risk analyses among men who started on anti-androgen monotherapy (AA) in competing risk analyses.

Figure 2. First event of conversion from AA to GnRH agonist, death from other causes or death from PCa assessed in competing risk analyses among men who started on anti-androgen monotherapy (AA) in competing risk analyses.

Table 1. Baseline characteristics of men in PCBaSe 3.0 diagnosed with high-risk and regionally metastatic prostate cancer in 2006–2012 and treated with anti-androgen monotherapy or GnRH agonists.

Figure 3. Cumulative probability of death from PCa or death from other causes for men on anti-androgen monotherapy (AA) and men on GnRH agonists.

Figure 3. Cumulative probability of death from PCa or death from other causes for men on anti-androgen monotherapy (AA) and men on GnRH agonists.

Table 2. Risk of death from prostate cancer or death from all causes in men on primary anti-androgen monotherapy or GnRH agonists.

Figure 4. Probability of PCa death and death from all causes following propensity score matched for men on anti-androgen monotherapy (AA) and GnRH agonists, assessed with 1-Kaplan-Meier estimates.

Figure 4. Probability of PCa death and death from all causes following propensity score matched for men on anti-androgen monotherapy (AA) and GnRH agonists, assessed with 1-Kaplan-Meier estimates.

Table 3. Risk of death from prostate cancer or death from all causes for men on primary GnRH agonists or anti-androgen monotherapy (AA, reference in analyses) following propensity score matching.