Changes in incidence trends of meningioma in Finland, 1990–2017: analysis of Finnish Cancer Registry data

Figures & data

Table 1. Clinical characteristics of meningioma cases, Finland 1990–2017 (N = 9842).

	Women	Men	Totaln
	n	n	n	%
Diagnostic confirmation
Histology of a primary tumor	5872	1967	7839	79.6
Autopsy, includes histological sample	719	314	1033	10.5
Clinical investigation	595	177	772	7.8
Unknown (includes DCO 1953–2014)	136	44	180	1.8
Death certificate only (2015–2017)	15	3	18	0.2
Autopsy only
No	6878	2290	9168	93.2
Yes	459	215	674	6.8
Types of meningioma
Meningioma, NOS	4891	1615	6506	66.1
Unclassified	761	242	1003	10.2
Meningothelial meningioma	541	222	763	7.8
Transitional meningioma	439	130	569	5.8
Atypical meningioma	298	196	494	5.0
Fibrous meningioma	308	58	366	3.7
Psammomatous meningioma	62	16	78	0.8
Angiomatous meningioma	29	23	52	0.5
Papillary meningioma	8	3	11	0.1
Total	7337	2505	9842	100.0

Figure 1. Number of cases and incidence of meningiomas in Finland by 4-year period during 1990–2017 by sex.

Figure 2. Incidence rate ratio of meningiomas by 10-year age group (with 95% confidence interval, ages 0–19 as the reference group), Finland 1990–2017.

Figure 3. Annual age-standardized incidence rates per 100,000 by sex in Finland during 1990–2017 with 95% confidence intervals.

Figure 4. Joinpoint analyses of meningioma incidence rates in women (A) and men (B), Finland 1990–2017.

Table

		1990–1993			1994–1997			1998–2001			2002–2005			2006–2009			2010–2013			2014–2017
Sex	Age group	I	95% CI		I	95% CI		I	95% CI		I	95% CI		I	95% CI		I	95% CI		I	95% CI
			Lower	Upper		Lower	Upper		Lower	Upper		Lower	Upper		Lower	Upper		Lower	Upper		Lower	Upper
Women	0–19	0.12	0.09	0.15	0.08	0.06	0.10	0.20	0.16	0.24	0.17	0.13	0.20	0.13	0.09	0.16	0.08	0.06	0.11	0.09	0.06	0.11
	20–29	0.51	0.47	0.56	0.87	0.80	0.93	1.13	1.06	1.20	0.70	0.64	0.75	1.23	1.16	1.31	0.68	0.63	0.73	0.83	0.77	0.89
	30–39	3.46	3.34	3.59	3.82	3.69	3.95	4.53	4.38	4.68	4.40	4.25	4.55	4.98	4.81	5.14	4.61	4.45	4.76	3.82	3.68	3.96
	40–49	7.72	7.53	7.91	9.83	9.62	10.05	10.09	9.87	10.32	10.66	10.43	10.90	11.2	10.96	11.44	10.19	9.96	10.43	11.76	11.50	12.02
	50–59	13.03	12.74	13.31	16.25	15.95	16.56	16.72	16.44	17.01	18.19	17.91	18.47	17.43	17.16	17.71	16.71	16.43	16.99	16.25	15.97	16.53
	60–69	14.8	14.53	15.07	18.84	18.53	19.14	22.9	22.57	23.24	22.70	22.37	23.02	22.06	21.76	22.36	21.94	21.66	22.22	19.02	18.77	19.27
	70+	15.02	14.72	15.33	19.49	19.16	19.82	26.04	25.67	26.42	24.62	24.27	24.97	27.62	27.25	27.98	23.47	23.15	23.80	22.95	22.64	23.26
Men	0–19	0.11	0.09	0.14	0.11	0.09	0.14	0	0	0	0.20	0.16	0.24	0.16	0.13	0.19	0.32	0.27	0.37	0.16	0.13	0.20
	20–29	0.28	0.25	0.31	0.45	0.41	0.50	0.54	0.49	0.59	0.52	0.47	0.57	1.03	0.96	1.09	0.43	0.39	0.47	0.72	0.66	0.77
	30–39	1.19	1.12	1.26	1.54	1.46	1.63	1.07	1.00	1.14	1.46	1.37	1.54	0.98	0.91	1.05	0.29	0.25	0.33	1.11	1.03	1.18
	40–49	2.41	2.30	2.51	3.13	3.01	3.24	2.76	2.64	2.87	3.30	3.17	3.43	2.45	2.34	2.56	2.65	2.53	2.77	3.02	2.89	3.15
	50–59	4.12	3.96	4.29	4.32	4.16	4.47	4.45	4.30	4.59	6.25	6.09	6.42	6.52	6.35	6.69	5.00	4.85	5.15	4.67	4.52	4.82
	60–69	7.84	7.62	8.05	6.49	6.29	6.68	8.85	8.63	9.07	9.17	8.96	9.39	9.26	9.06	9.46	8.58	8.40	8.76	9.25	9.07	9.43
	70+	10.19	9.84	10.55	13.14	12.76	13.52	15.21	14.82	15.59	14.45	14.09	14.81	13.60	13.27	13.92	13.61	13.30	13.91	14.08	13.79	14.37
Total	0–19	0.12	0.10	0.14	0.10	0.08	0.11	0.10	0.08	0.12	0.18	0.16	0.21	0.14	0.12	0.17	0.21	0.18	0.23	0.13	0.10	0.15
	20–29	0.39	0.37	0.42	0.65	0.63	0.69	0.83	0.79	0.87	0.61	0.57	0.64	1.13	1.08	1.18	0.55	0.52	0.59	0.77	0.73	0.81
	30–39	2.30	2.23	2.37	2.66	2.59	2.74	2.77	2.69	2.85	2.90	2.81	2.98	2.93	2.84	3.02	2.39	2.31	2.47	2.42	2.34	2.50
	40–49	5.01	4.90	5.11	6.42	6.31	6.54	6.38	6.25	6.50	6.94	6.81	7.07	6.77	6.64	6.90	6.37	6.24	6.50	7.31	7.17	7.45
	50–59	8.64	8.47	8.81	10.32	10.15	10.49	10.57	10.41	10.74	12.21	12.05	12.38	11.99	11.83	12.15	10.88	10.72	11.04	10.47	10.31	10.62
	60–69	11.69	11.52	11.87	13.15	12.97	13.34	16.31	16.10	16.52	16.26	16.06	16.46	15.88	15.70	16.07	15.45	15.29	15.62	14.29	14.13	14.44
	70+	13.44	13.20	13.67	17.35	17.11	17.60	22.22	21.95	22.50	20.88	20.62	21.14	22.26	22.00	22.51	19.57	19.34	19.80	19.30	19.09	19.52

I: incidence per 100,000; 95% CI: 95% confidence interval.

Data availability statement

The data (meningioma cases and incidence) are available from registry authorities, as according to Finnish regulations, researchers are not allowed to forward confidential non-anonymous health data to any third parties.