Figures & data
Table 1. Patient, disease and treatment characteristics in the cohort eligible for analysis.
Table 2. Proportions of patients with MSP symptoms with and without worsening compared to baseline condition.
Table 3. Proportion of patient with MSP gastrointestinal and systemic (pain, fatigue, and insomnia) symptoms defined using a stricter threshold for persistence (score ≥3).
Figure 1. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP urinary symptoms.
![Figure 1. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP urinary symptoms.](/cms/asset/7b88fd20-2d51-479e-b1c9-261af05316a5/ionc_a_2259597_f0001_c.jpg)
Figure 2. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP gastrointestinal symptoms.
![Figure 2. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP gastrointestinal symptoms.](/cms/asset/bbfd4cee-2dc0-48d6-886d-ee04c00f4591/ionc_a_2259597_f0002_c.jpg)
Figure 3. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP pain, fatigue, and insomnia.
![Figure 3. Mean and 95% confidence intervals for EORTC-C30 Global health/QOL during late follow-up for patients without and with MSP pain, fatigue, and insomnia.](/cms/asset/2220d463-db46-4dae-ba38-c660abe0c4ba/ionc_a_2259597_f0003_c.jpg)
Figure 4. Mean QOL deteriorations over 5 years for patients with MSP symptoms. Values are shown when statistically significance was found with LMM. Clinical relevance was assigned according the guidelines to interpret changes in EORTC-C30 scores [Citation35].
![Figure 4. Mean QOL deteriorations over 5 years for patients with MSP symptoms. Values are shown when statistically significance was found with LMM. Clinical relevance was assigned according the guidelines to interpret changes in EORTC-C30 scores [Citation35].](/cms/asset/9312404d-c180-4abb-9a97-0c42e4378657/ionc_a_2259597_f0004_b.jpg)
Supplemental Material
Download PDF (88.7 KB)Supplemental Material
Download PDF (156.8 KB)Supplemental Material
Download PDF (110.8 KB)Supplemental Material
Download PDF (221.6 KB)Data availability statement
The data that support the findings of this study are available from the corresponding author, SS, upon reasonable request.