Impact of OAB symptoms on work, quality of life and treatment-seeking behavior in Brazil

Figures & data

Figure 1. Association of demographic factors and comorbidities with overactive bladder in men and women. Abbreviation. OAB, overactive bladder. Statistically non-significant data are not shown.

Figure 2. Chance of missing work in men and women with a possible diagnosis of overactive bladder: forest plot of multiple regression models; adjusted odds ratios (95% CI). Statistically non-significant data are not shown.

Figure 3. Chance of limitation of daily and leisure activities in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval; SUI, stress urinary incontinence; UUI, urgency urinary incontinence. Statistically non-significant data are not shown.

Figure 4. Chance of worse QoL due to LUTS in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval; LUTS, lower urinary tract symptoms; QoL, quality of life; SUI, stress urinary incontinence. Statistically non-significant data are not shown.

Figure 5. Chance of seeking treatment in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval. Statistically non-significant data are not shown.

Figure 6. Chance of treatment in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval. Statistically non-significant data are not shown.

Figure 7. Chance of treatment discontinuation in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval. Statistically non-significant data are not shown.

Figure 8. Chance of treatment dissatisfaction in men and women with a possible diagnosis of overactive bladder: Forest plot of multiple regression models; adjusted odds ratios (95% CI). Abbreviations. CI, confidence interval; UUI, urgency urinary incontinence. Statistically non-significant data are not shown.

Table 1. Impact of OAB on work, daily and leisure activities; treatment seeking, treatment, treatment satisfaction and treatment discontinuation by age in men with a possible diagnosis of OAB.

	Age
	≤49		50–59		60–69		70+		Total
	N	%	N	%	N	%	N	%	N	%	p
Missing work	6	4.1	2	0.9	2	1.0	3	2.6	12	2.0	.181
Missing leisure activities/Impairing daily activities	30	20.3	18	9.2	23	15.2	17	17.4	88	14.8	.418
Treatment seeking	25	17.3	56	27.9	79	52.4	49	50.1	209	35.1	<.001
Treatment	12	8.3	44	22.2	74	49.3	43	44.1	174	29.1	<.001
Treatment–satisfaction^a	6	55.8	17	50.2	54	75.8	24	64.8	101	66.1	.436
Treatment discontinuation^a	2	18.3	10	22.8	2	3.2	6	13.4	21	11.8	.128

^aOnly those who have received treatment.

All numbers presented are weighted; subgroups might or might not be equal to total N because of rounding, weighted values, or missing data.

p–descriptive level of chi-square test considering the sampling plan.

Abbreviations. OAB, overactive bladder.

Table 2. Impact of OAB on work, daily and leisure activities; treatment seeking, treatment, treatment satisfaction and treatment discontinuation by age in women with a possible diagnosis of OAB.

	Age
	≤49		50–59		60–69		70+		Total
	N	%	N	%	N	%	N	%	N	%	p
Missing work	10	4.9	19	7.5	6	5.4	9	8.0	44	6.5	.836
Missing leisure activities/Impairing daily activities	50	26.2	59	22.9	32	29.0	31	28.4	173	25.8	.822
Treatment seeking	76	39.6	97	37.6	64	58.1	55	50.2	292	43.6	.067
Treatment	66	34.5	78	30.4	59	52.8	47	42.9	250	37.3	.041
Treatment–satisfaction^a	37	62.1	43	60.3	29	66.4	34	80.6	143	65.9	.464
Treatment discontinuation^a	6	9.5	7	9.2	15	24.9	5	11.4	33	13.4	.232

^aOnly those who have received treatment.

All numbers presented are weighted; subgroups might or might not be equal to total N because of rounding, weighted values, or missing data.

p–descriptive level of chi-square test considering the sampling plan.

Abbreviations. OAB, overactive bladder.

Data availability

Access to anonymized individual participant level data will not be provided for this trial as it meets one or more of the exceptions described on www.clinicalstudydatarequest.com under “Sponsor Specific Details for Astellas”.