Figures & data
Figure 1. Study design for the main analysis. Abbreviations. IBD, inflammatory bowel disease; UC, ulcerative colitis.
![Figure 1. Study design for the main analysis. Abbreviations. IBD, inflammatory bowel disease; UC, ulcerative colitis.](/cms/asset/8bbeded5-e216-40af-8d2f-d471def74559/icmo_a_1771293_f0001_b.jpg)
Figure 2. Sample selection for the UC and non-IBD cohorts. Abbreviations. IBD, inflammatory bowel disease; ICD-9-CM, International Classification of Disease, 9th revision, Clinical Modification; ICD-10-CM, International Classification of Disease, 10th revision, Clinical Modification; UC, ulcerative colitis. Notes: (1) Unspecified colitis (ICD-9 CM code: 558.xx, ICD-10 CM code: K52.xx) was not used to identify patients with UC. (2) A random sample of 20% of patients without a recorded diagnosis of IBD during the study period (1 January 1999 to 31 March 2017) was selected from the OptumHealth Care Solutions, Inc employer claims database.
![Figure 2. Sample selection for the UC and non-IBD cohorts. Abbreviations. IBD, inflammatory bowel disease; ICD-9-CM, International Classification of Disease, 9th revision, Clinical Modification; ICD-10-CM, International Classification of Disease, 10th revision, Clinical Modification; UC, ulcerative colitis. Notes: (1) Unspecified colitis (ICD-9 CM code: 558.xx, ICD-10 CM code: K52.xx) was not used to identify patients with UC. (2) A random sample of 20% of patients without a recorded diagnosis of IBD during the study period (1 January 1999 to 31 March 2017) was selected from the OptumHealth Care Solutions, Inc employer claims database.](/cms/asset/96fdbaf3-2d5f-4c0f-9fda-9288a31d0911/icmo_a_1771293_f0002_b.jpg)
Table 1. Baseline characteristics in the UC and non-IBD cohorts.
Figure 3. All-cause HRU and work loss days in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; ED, emergency department; HRU, healthcare resource utilization; IBD, inflammatory bowel disease; IP, inpatient; IRR, incidence rate ratio; OP, outpatient; PPPY, per patient per year; UC, ulcerative colitis.
![Figure 3. All-cause HRU and work loss days in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; ED, emergency department; HRU, healthcare resource utilization; IBD, inflammatory bowel disease; IP, inpatient; IRR, incidence rate ratio; OP, outpatient; PPPY, per patient per year; UC, ulcerative colitis.](/cms/asset/2186e858-d33e-4df0-a8a9-05352e03588b/icmo_a_1771293_f0003_b.jpg)
Figure 4. Direct (A) and indirect (B) healthcare costs (2017 USD) among patients in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; IBD, inflammatory bowel disease; MCD, mean cost difference; PPPY, per patient per year; UC, ulcerative colitis.
![Figure 4. Direct (A) and indirect (B) healthcare costs (2017 USD) among patients in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; IBD, inflammatory bowel disease; MCD, mean cost difference; PPPY, per patient per year; UC, ulcerative colitis.](/cms/asset/cfc02d83-f76e-4fc7-a07e-03c3cd213d65/icmo_a_1771293_f0004_c.jpg)
Table 2. Medication use and comorbidities of patients in the UC cohort (indicators for subgroups).