Figures & data
Figure 1. Study design for the main analysis. Abbreviations. IBD, inflammatory bowel disease; UC, ulcerative colitis.
Figure 2. Sample selection for the UC and non-IBD cohorts. Abbreviations. IBD, inflammatory bowel disease; ICD-9-CM, International Classification of Disease, 9th revision, Clinical Modification; ICD-10-CM, International Classification of Disease, 10th revision, Clinical Modification; UC, ulcerative colitis. Notes: (1) Unspecified colitis (ICD-9 CM code: 558.xx, ICD-10 CM code: K52.xx) was not used to identify patients with UC. (2) A random sample of 20% of patients without a recorded diagnosis of IBD during the study period (1 January 1999 to 31 March 2017) was selected from the OptumHealth Care Solutions, Inc employer claims database.
Table 1. Baseline characteristics in the UC and non-IBD cohorts.
Figure 3. All-cause HRU and work loss days in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; ED, emergency department; HRU, healthcare resource utilization; IBD, inflammatory bowel disease; IP, inpatient; IRR, incidence rate ratio; OP, outpatient; PPPY, per patient per year; UC, ulcerative colitis.
Figure 4. Direct (A) and indirect (B) healthcare costs (2017 USD) among patients in the UC and non-IBD cohorts. *Statistical significance at the .05 level. Abbreviations. CI, confidence interval; IBD, inflammatory bowel disease; MCD, mean cost difference; PPPY, per patient per year; UC, ulcerative colitis.
Table 2. Medication use and comorbidities of patients in the UC cohort (indicators for subgroups).
Figure 5. Direct and indirect healthcare costs (2017 USD) among subgroups of patients with UC. Abbreviations. PPPY, per patient per year; UC, ulcerative colitis
