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Respiratory Medicines

Toward a better understanding of severe asthma phenotypes in Latin America: results from the PREPARE study

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Pages 627-638 | Received 11 Oct 2022, Accepted 26 Jan 2023, Published online: 23 Feb 2023

Figures & data

Table 1. Baseline demographic and lifestyle characteristics of the Latin American study population (N = 461).

Table 2. Disease characteristics of the Latin American study population (N = 461).

Figure 1. Differences in the number of severe exacerbations evaluated using the ANOVA test across the Latin American study population with atopic phenotype (total serum IgE >100 IU/mL and BEC <300 cells/mm3) and with eosinophilic phenotype (total serum IgE ≤100 IU/mL and BEC ≥300 cells/mm3). Abbreviations. ANOVA, analysis of variance; IgE, immunoglobulin E.

Figure 1. Differences in the number of severe exacerbations evaluated using the ANOVA test across the Latin American study population with atopic phenotype (total serum IgE >100 IU/mL and BEC <300 cells/mm3) and with eosinophilic phenotype (total serum IgE ≤100 IU/mL and BEC ≥300 cells/mm3). Abbreviations. ANOVA, analysis of variance; IgE, immunoglobulin E.

Table 3. Hematological assessments in the Latin American study population (N = 461).

Table 4. Baseline demographic and lifestyle characteristics of the Latin American study population (N = 461) by BECs and serum IgE concentrations levels.

Table 5. Disease characteristics of the Latin American study population (N = 461) by BECs and serum IgE concentrations levels.

Table 6. Pattern of OCS use by BECs and serum IgE concentrations in the Latin American study population (N = 461).

Table 7. Asthma treatments prescribed in the previous 12 months to the Latin American study population (N = 461).

Table 8. Asthma symptom control in the Latin American study population (N = 461).

Supplemental material

PREPARE_manuscript_supplemental_file.docx

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Data availability statement

Data underlying the findings described in this manuscript may be obtained in accordance with AstraZeneca’s data sharing policy described at https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure.