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Pain Medicine

Analgesic onset and efficacy of a fast-acting formulation of acetaminophen in a postoperative dental impaction pain model

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Pages 267-277 | Received 15 Feb 2023, Accepted 11 Dec 2023, Published online: 01 Jan 2024

Figures & data

Figure 1. Patient disposition for Studies 1 and 2.

Figure 1. Patient disposition for Studies 1 and 2.

Figure 2. Kaplan-Meier plots of time to confirmed perceptible pain relief in Study 1 (a) and Study 2 (b).

Figure 2. Kaplan-Meier plots of time to confirmed perceptible pain relief in Study 1 (a) and Study 2 (b).

Table 1. Summary of pain relief, pain intensity differences, use of rescue medication, and subject global evaluation during the 6 h treatment period.

Figure 3. Kaplan-Meier plots of time to meaningful pain relief in Study 1 (A) and Study 2 (B).

Figure 3. Kaplan-Meier plots of time to meaningful pain relief in Study 1 (A) and Study 2 (B).

Figure 4. Time course of pain intensity difference (PID) scores for each treatment in Study 1 (A) and Study 2 (B). Data presented as least squares mean (LSMean) ± standard error (SE).

Figure 4. Time course of pain intensity difference (PID) scores for each treatment in Study 1 (A) and Study 2 (B). Data presented as least squares mean (LSMean) ± standard error (SE).

Table 2. Plasma concentrations (μg/mL) following a single oral dose of study drug.

Supplemental material

Supplement Materials SUBMIT.docx

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Dental Pain 1_2 Supplemental Figure.docx

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Supplemental Table Demog SUBMIT.docx

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