Distant metastasis in patients with myxofibrosarcoma

Figures & data

Table 1. Clinical information of 16 patients with myxofibrosarcoma.

Case	Age	Sex	Tumor location	Tumor size (cm)	FNCLCC grade	AJCC stage	Margin	Treatment excluding surgery	Recurrence	Metastasis (months)^a	Treatment for metastasis	Follow-up period (months)	Outcome
1	82	F	Thigh	10	2	2	Wide	–	+	Lung (11)	Radiation	14	DOD
2	87	F	Buttock	7	3	3	Wide	–	–	Lymph node (32)	Surgery	56	NED
3	85	M	Forearm	5	1	1	Wide	–	–	Lung (8)	–	22	DOD
4	78	F	Thigh	1.5	1	1	Non-surgery	Radiation		Lung (14)	–	16	DOD
5	61	M	Inguinal	10	1	1	Non-surgery	Radiation		Lymph node, muscle (39)	Radiation	62	AWD
6	64	M	Upper arm	10	2	2	Wide	–	+	Lymph node (13)	Radiation, chemotherapy	142	NED
7	46	M	Upper arm	7.7	1	1	Wide	–	–	Lung (12)	Surgery, chemotherapy	66	NED
8	81	M	Chest wall	7	2	2	Intraregional	Radiation	+	Lung (8)	Surgery, radiation	90	DOD
9	79	M	Lower leg	3.5	2	2	Wide	–	–	Lung, peritoneum (19)	–	20	AWD
10	69	M	Lower leg	5	3	3	Wide	Radiation	–	Lymph node (59)	Radiation, chemotherapy	77	NED
11	87	F	Forearm	10	2	2	Intraregional	–	+	Lung (12)	–	17	DOD
12	78	F	Buttock	22	1	1	Intraregional	Radiation	+	Subcutaneous, lung, bone (15)	–	23	DOD
13	87	M	Lower leg	8.9	3	4	Wide	–	–	Lung (0)	–	8	DOD
14	89	F	Lower leg	5	3	3	Wide	Radiation	–	Lymph node (21)	Surgery	31	NED
15	65	F	Inguinal	5.5	1	1	Wide	Radiation	–	Lung (9)	Chemotherapy	23	NED
16	87	M	Shoulder	12.7	1	1	Non-surgery	Radiation		Lung (6)	–	19	AWD

^a Time until the first metastasis after the initial examination.

AWD: alive with disease; DOD: dead of disease; NED: no evidence of disease.

Figure 1. Kaplan–Meier overall survival curves according to regions of metastasis.

Table 2. Univariate logistic regression analysis between the two groups.

	Lung group	Lymph node group	95% CI	p value
Age	77.7 ± 12.3	74 ± 13.1	−17.54 to 24.99	0.59
Sex			−0.844 to 0.953	0.734
Male	6	2
Female	5	3
Tumor location			−0.961 to 0.707	0.942
Trunk	2	3
Extremity	3	8
Tumor size (cm)	85.3 ± 55.0	74.0 ± 25.1	−70.85 to 93.40	0.6724
FNCLCC grade			−2.132 to 0.422	0.0538
Grade 1	6	1
Grades 2 and 3	5	4
AJCC stage			−2.318 to 0.791	0.1445
Stages 1 and 2	10	2
Stages 3 and 4	1	3
Time until first metastasis (months)	10.3 ± 5.0	32.8 ± 17.7	−40.07 to −4.804	0.0498

Values are expressed as the number of patients or mean ± SD.

95% CI = 95% confidence interval.