Specific toxicity in six rodent species from China of a new modified norbormide

Figures & data

Figure 1. Average percentage mortality caused by DR8 across all dose groups for male, female and both sexes of Rattus species, R.losea, R.n.norvegicus and R.n.caraco (for R.n.caraco, 15 mg/kg was exclusive); no differences were found either inter-species/subspecies of Rattus or between sexes of same species.

Table 1. Mortality (% of deaths) of six rodent species dosed with different levels of DR8 (n = 6 per group).

Rodent species	Mortality (% of deaths) of rodents at different doses (mg/kg)
	10	15	20	30	50	100	200
R.losea	16.67	–	33.33	50	83.33	83.33	–
R.n.norvegicus	0	–	16.67	66.67	83.33	83.33	–
R.n.caraco	0	50	83.33	100	100	100	–
B.indica	0	–	–	–	–	–	0
L.brandtii	–	–	–	–	–	–	0
M.fortis	–	–	–	–	–	–	0

Note: ‘–’ denotes no rodent was tested at this dose.

Figure 2. Average time to death (hours) for Rattus species, R.losea, R.n.norvegicus and R.n.caraco, at increasing doses of DR8. *Means a significant difference; ns is no significant difference.

Figure 3. LD₅₀ for the Rattus species, R.losea, R.n.norvegicus and R.n.caraco, calculated by regression of probits converted from percentage mortalities against and log-doses of DR8.