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Avian Pathology Volume 35, 2006 - Issue 2
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Original Articles

Heterophil cytokine mRNA profiles from genetically distinct lines of chickens with differential heterophil-mediated innate immune responses

Christina L. Swaggerty United States Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, 2881 F&B Road, College Station, TX, 77845, USA
,
Pete Kaiser Institute for Animal Health, Compton, Berkshire, RG20, 7NN, UK
,
Lisa Rothwell Institute for Animal Health, Compton, Berkshire, RG20, 7NN, UK
,
Igal Y. Pevzner Cobb–Vantress, Inc., Siloam Springs, AR, 72761-1030, USA
&
Michael H. Kogut United States Department of Agriculture, Agricultural Research Service, Southern Plains Agricultural Research Center, 2881 F&B Road, College Station, TX, 77845, USACorrespondence[email protected]
Pages 102-108 | Published online: 18 Jan 2007

Figures & data

Figure 1.  Quantitation of IL-6 mRNA expression in heterophils isolated from (1a) line A chickens and (1b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in IL-6 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 1.  Quantitation of IL-6 mRNA expression in heterophils isolated from (1a) line A chickens and (1b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in IL-6 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 2.  Quantitation of CXCLi2 mRNA expression in heterophils isolated from (2a) line A chickens and (2b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in CXCLi2 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 2.  Quantitation of CXCLi2 mRNA expression in heterophils isolated from (2a) line A chickens and (2b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in CXCLi2 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 3.  Quantitation of IL-18 mRNA expression in heterophils isolated from (3a) line A chickens and (3b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in IL-18 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 3.  Quantitation of IL-18 mRNA expression in heterophils isolated from (3a) line A chickens and (3b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in IL-18 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 4.  Quantitation of TGF-β4 mRNA expression in heterophils isolated from (4a) line A chickens and (4b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in TGF-β4 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

Figure 4.  Quantitation of TGF-β4 mRNA expression in heterophils isolated from (4a) line A chickens and (4b) line B chickens on days 1, 14, and 28 post-hatch. Data are expressed as the fold change in TGF-β4 mRNA levels when treated samples (S. enteritidis [SE], NCS-OpSE, and IgY-OpSE) were compared with control heterophils treated with RPMI. Error bars show the standard error of the mean from triplicate experiments.

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