Identification of avian bornavirus in a Himalayan monal (Lophophorus impejanus) with neurological disease

Figures & data

Figure 1. Histologic changes in brain and sciatic nerve of a Himalayan monal (Lophophorus impejanus) from which avian bornavirus genotype 4 was identified. (a) Brain, numerous lymphocytes and plasma cells expanding Virchow-Robin space (H&E stain). (b) Brain, marked neuropil vacuolation, gemistocytic astrocytes (white arrow) and swollen axons (black arrow; H&E stain). (c) Brain, positive immunohistochemical staining for ABV antigen in neuronal nuclei (black arrows) using rabbit polyclonal antiserum raised against ABV nucleocapsid protein. (d) Sciatic nerve, multifocal dilated myelin sheaths (black arrows) and myelin macrophage (white arrow; H&E stain)

Figure 2. Phylogenetic tree illustrating the phylogenetic relationships among the partial ABV matrix protein gene nucleotide sequences of a Himalayan monal (13-077270-0003) and a white-bellied caique (13-099226-0003) from the same aviary, and ABV genotype 1-5 sequences from a variety of psittacine birds as published in GenBank

Figure 3. Pairwise sequence comparisons among the partial ABV matrix protein gene nucleotide sequences of a Himalayan monal (13-077270-0003) and white-bellied caique (13-099226-0003) from the same aviary, and ABV genotype 1-5 sequences from a variety of psittacine birds as published in GenBank