210
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Harmonic analysis of peripheral pulse for screening subjects at high risk of diabetes

, , ORCID Icon, , , & show all
Pages 437-443 | Received 15 Feb 2017, Accepted 24 Apr 2017, Published online: 06 Jun 2017
 

Abstract

Power spectral density (PSD) of peripheral pulses in human has been investigated in the past for its clinical applications. Continuing the efforts, data acquired using Peripheral Pulse Analyser in research projects sponsored by Board of Research in Nuclear Sciences in 207 control subjects, 18 descendants of diabetic patients and 22 patients with systemic hypertension have been subjected to PSD analysis for its study of harmonics. Application software, named Pulse Harmonic Analyser specifically developed for this work, selected 131,072 samples from each data file, obtained PSD, derived 52 PHA parameters and saved them in an Excel sheet. Coefficient of variation in control data was reduced significantly by application of Central Limit Theorem, which enabled use of parametric methods for statistical analysis of the observations. Data in hypertensive patients have shown significant difference in comparison to that of controls in eight parameters at low values of α and β. Data in offspring of diabetic patients also have shown significant difference in one parameter indicating its usefulness in screening subjects with genetic disposition of acquiring Type-II Diabetes. PHA analysis has also yielded sub-harmonic components, which are related to combined variability in the heart rate, pulse volume and pulse morphology and has a potential to become method of choice for real time variability monitoring.

Acknowledgements

Authors are grateful to Board of Research in Nuclear Sciences, Department of Atomic Energy, Government of India, Dr. Srinath Rao, Professor, Father Muller Homeopathic Medical College, Mangalore and Dr. Jayaprakash Alva, Dean, Father Muller Medical College, Mangalore for permitting to use their PPA data for the present analysis. Authors also thank Smt. Anita Behere, Head Electronics Division (ED), Bhabha Atomic Research Centre (BARC) and Dr. Santosh Narayankhedkar, Principal, MGMCET, for their encouragement and support in execution of BRNS projects and Shri Vineet Sinha, ED, BARC for providing PPA instruments for recording of peripheral pulses.

Disclosure statement

No potential conflict of interest was reported by the authors.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 706.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.