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Journal of Environmental Science and Health, Part B
Pesticides, Food Contaminants, and Agricultural Wastes
Volume 52, 2017 - Issue 7
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Articles

The impact of pesticides on oxidative stress level in human organism and their activity as an endocrine disruptor

Agata Jabłońska-TrypućFaculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Białystok, PolandCorrespondence[email protected]
,
Elżbieta WołejkoFaculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Białystok, Poland
,
Urszula WydroFaculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Białystok, Poland
&
Andrzej ButarewiczFaculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Białystok, Poland
Pages 483-494 | Received 25 Nov 2016, Accepted 09 Feb 2017, Published online: 25 May 2017
 
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ABSTRACT

Pesticides cause serious environmental and health problems both to humans and animals. The aim of this review is to discuss selected herbicides and fungicides regarding their mode of action and their influence on basic oxidative stress parameters and endocrine disruption properties tested in selected cell cultures in vitro. Because of numerous difficulties which animal studies are subject to, cell cultures are an excellent experimental model reflecting human exposure to different pesticides through all relevant routes. This experimental model can be used to monitor aggregate and cumulative pesticide exposures.

Funding

This work is financially supported by project number S/WBiIŚ/3/2015.

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