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DESIGN OF EXPERIMENTS

Optimal One-Way Random Effects Designs for the Intraclass Correlation Based on Confidence Intervals

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Pages 2009-2023 | Received 02 Oct 2003, Accepted 15 Apr 2005, Published online: 02 Sep 2006
 

ABSTRACT

Confidence intervals for the intraclass correlation coefficient (ρ) are used to determine the optimal allocation of experimental material in one-way random effects models. Designs that produce narrow intervals are preferred since they provide greater precision to estimate ρ. Assuming the total cost and the relative cost of the two stages of sampling are fixed, the authors investigate the number of classes and the number of individuals per class required to minimize the expected length of confidence intervals. We obtain results using asymptotic theory and compare these results to those obtained using exact calculations. The best design depends on the unknown value of ρ. Minimizing the maximum expected length of confidence intervals guards against worst-case scenarios. A good overall recommendation based on asymptotic results is to choose a design having classes of size 2 + √4 + 3r, where r is the relative cost of sampling at the class-level compared to the individual-level. If r = 0, then the overall cost is the sample size and the recommendation reduces to a design having classes of size 4.

Mathematics Subject Classification:

Acknowledgments

The authors extend their appreciation to the referees for their valuable suggestions.

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