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Hemoglobin
international journal for hemoglobin research
Volume 31, 2007 - Issue 1
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Short Communication

Four Cases of Hb Q-H Disease Found in Southern China

Dongzhi Li Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of ChinaCorrespondence[email protected]
,
Can Liao Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of China
,
Xingmei Xie Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of China
,
Huizhu Zhong Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of China
&
Jian Li Prenatal Diagnostic Center, Guangzhou Maternal & Neonatal Hospital, Guangzhou Medical College, Guangzhou, Guangdong, People's Republic of China
Pages 109-111 | Received 03 Aug 2006, Accepted 10 Aug 2006, Published online: 07 Jul 2009
 
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Abstract

Four Chinese patients with Hb Q-H disease were identified during thalassemia screening. The main hematological characteristics of Hb Q-H disease are that Hb A is absent, and Hb Q-Thailand (also known as G-Taichung, Mahidol, Kurashiki-I and Asabara) accounts for the majority of the total hemoglobin (Hb). The phenotype of this disorder is similar to that of deletional Hb H (β4) disease.

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