REVIEW: Iodine Determination by Inductively Coupled Plasma Spectrometry

Abstract

Iodine is a chemical element with critical physiological roles and its determination using instrumental analysis is not trivial. Inductively coupled plasma spectrometry associated with either optical emission (ICP-OES) or mass spectrometry (ICP-MS) may be employed, but each alternative presents limitations considering iodine behavior in argon plasma and the occurrence of interferences. Sample preparation is also a critical issue when using sample introduction by pneumatic nebulization due to memory effects. This critical review discusses the literature dealing with sample preparation followed by ICP-OES or ICP-MS for iodine determination in a plethora of samples. It is shown that the best figures of merit may be reached using sample preparation in alkaline medium followed by ICP-MS measurements.

Keywords:

• iodine
• ICP–OES
• ICP–MS
• sample preparation
• alkaline medium

Notes

^aLOD: limit of detection.

^bCRMs: certified reference materials.

^cMultiwave: pressure and temperature controlled equipment for microwave-assisted sample digestion in closed vessels.

^dPMD: pressure controlled equipment for microwave-assisted sample digestion in closed vessels.

^eHPA: high-pressure asher.

^fTMAH: tetramethylammonium hydroxide.

^gIS: internal standard.

^hNAA: neutron activation analysis.

ⁱTXRF: total reflection X-ray fluorescence.

^jCFA-C: water-soluble tertiary amines.

^kPC-NAA: pre-irradiation combustion-neutron activation analysis.

^mSAM: standard additions method.

^aLOD: limit of detection.

^bCRMs: certified reference materials.

^cSAM: standard additions method.

^dIS: internal standard.