A Food-Derived Dietary Supplement Containing a Low Dose of Iron Improved Markers of Iron Status Among Nonanemic Iron-Deficient Women

Figures & data

Figure 1. Patient flow diagram.

Table 1. Baseline Participant Characteristics (n = 23).

Variable	Value^*
Age (years)	29.7 (7.9)
BMI (kg/m^2)	24.4 (6.9)
Race
White	52% (12/23)
Black	44% (10/23)
Other	4% (1/23)
Highest education level
Associate, trade, or technical degree	13% (3/23)
College degree	35% (8/23)
Graduate/professional degree	52% (12/23)

Note.

* Values are mean (SD) or % (n/N).

BMI = body mass index.

Table 2. Markers of Iron Status.

Variable	Value	p value
Hemoglobin (g/dL)^*
Week 0	12.8 (0.8)
Week 8	13.2 (0.7)	0.004
Serum ferritin (μg/L)^*
Week 0	13.9 (5.0)
Week 8	21.1 (9.0)	< 0.001
Soluble transferrin receptor (mg/L)^**
Week 0	1.31 (0.97, 1.50)
Week 8	1.23 (1.04, 1.37)	0.04
Total body iron stores (mg/kg)^*
Week 0	6.77 (2.30)
Week 8	8.57 (1.93)	< 0.001

Note.

* Values are mean (SD) with p values determined by dependent samples t test.

** Values are median (interquartile range) with p values determined by Wilcoxon signed-rank test due to nonnormally distributed data.

Table 3. Fatigue and Energy During the Previous Week.

Variable	Value	p value
Fatigue severity^*
Week 0	2.6 (0.8)
Week 8	1.9 (0.6)	< 0.001
Fatigue frequency^*
Week 0	2.8 (0.9)
Week 8	1.8 (0.4)	< 0.001
Fatigue composite^**
Week 0	7.6 (4.2)
Week 8	3.5 (1.6)	< 0.001
Energy^*
Week 0	2.7 (0.6)
Week 8	3.3 (0.6)	< 0.001

Note.

* Values are mean (SD) on a 1–5 Likert scale with p values determined by dependent samples t test.

** Values are mean (SD) on a 1–25 Likert scale (fatigue severity × fatigue frequency) with p values determined by dependent samples t test.