A Review of Quality of Life Measures used in Surgical Outcomes for Stage I Lung Cancers

Abstract

This review summarizes the literature on QoL in early stage lung cancer patients who underwent surgery. PubMed and PsycINFO were searched. Twelve articles from 10 distinct studies were identified for a total of 992 patients. Five QoL measures were used. One study reported only on pre-surgical QoL, six only on post-surgical QoL and three studies reported on both pre- and post-surgical QoL. Timing for the administration of post-surgical QoL surveys varied. The literature on QoL in Stage I non-small-cell lung cancer patients is very sparse. Additional research is needed to explore the impact of different surgical approaches on QoL.

Keywords:

• CT Screening
• Surgery
• Quality of life
• Population norm
• Effect sizes

Acknowledgements

We would like to thank Mr. Gil Moskowitz (Icahn School of Medicine at Mount Sinai), who provided assistance in literature search and identification of relevant studies to be included in this review.

A generous gift by Sonia Lasry Gardner given in loving memory of her father, Moise Lasry, to support lung cancer research, outreach, and treatment and also by others.

Declaration of interest

Dr. Yankelevitz is a named inventor on a number of patents and patent applications relating to the evaluation of diseases of the chest including measurement of nodules. Some of these, which are owned by Cornell Research Foundation (CRF), are non-exclusively licensed to General Electric. As an inventor of these patents, Dr. Yankelevitz is entitled to a share of any compensation which CRF may receive from its commercialization of these patents. He is also an equity owner in Accumetra, a privately held technology company committed to improving the science and practice of image-based decision making. Dr. Yankelevitz also serves on the advisory board of GRAIL. Dr. Henschke is also an inventor of the patents and pending patents owned by Cornell Research Foundation (CRF). As of April 2009, she has divested herself of all royalties and other interests arising from these.

Additional information

Funding

The study was support by Cancer Center Grant P30CA196521.