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Original Article

PDTCM: a systems pharmacology platform of traditional Chinese medicine for psoriasis

, , , , , & show all
Pages 652-660 | Received 26 May 2017, Accepted 03 Jul 2017, Published online: 24 Aug 2017

Figures & data

Table 1. Statistics of molecular descriptors in PDTCM.

Table 2. Targets related to psoriasis for molecular docking.

Figure 1. An illustrated steps for classic formula “PSORI-CM01” (composed of seven herbs). Notes: It was achieved on the page of Herbal formula DIY.

Figure 1. An illustrated steps for classic formula “PSORI-CM01” (composed of seven herbs). Notes: It was achieved on the page of Herbal formula DIY.

Figure 2. Distribution in chemical space according to PCA of compounds in PDTCM and psoriatic drugs.

Figure 2. Distribution in chemical space according to PCA of compounds in PDTCM and psoriatic drugs.

Figure 3. Distribution of drug-like molecular descriptors of TCM.

Figure 3. Distribution of drug-like molecular descriptors of TCM.

Figure 4. Drug-target network of PDTCM. Notes: Triangle and dot represent molecules (n = 605) and targets (n = 38), respectively.

Figure 4. Drug-target network of PDTCM. Notes: Triangle and dot represent molecules (n = 605) and targets (n = 38), respectively.

Table 3. Top rank of potential compounds for psoriasis according to degree and betweenness centrality of MTN.

Figure 5. PCA of three clinical formulas.

Figure 5. PCA of three clinical formulas.

Table 4. Three formulas information about composed compounds and duplicate herbs.

Supplemental material

Supplementary_Table_S2.xlsx

Download MS Excel (27 KB)

Supplementary_Table_S1.xlsx

Download MS Excel (10.6 KB)

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