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Annals of Medicine Volume 55, 2023 - Issue 1
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Pulmonary Medicine

The effects of different inhalation therapies on less symptomatic chronic obstructive pulmonary disease patients in a Chinese population: a real-world study

Qing Songa Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Ling Lina Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Aiyuan Zhoud Center of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaView further author information
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Wei Chenga Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaORCID Iconhttps://orcid.org/0000-0003-1025-0591View further author information
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Cong Liua Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Yating Penga Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaORCID Iconhttps://orcid.org/0000-0003-2345-4059View further author information
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Zijing Zhoua Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Yuqin Zenga Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Dingding Denge Department of Respiratory Medicine, The First Attached Hospital of Shaoyang University, Shaoyang, Hunan, ChinaView further author information
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Dan Liuf Department of Respiratory, The Eighth Hospital in Changsha, Hunan, ChinaView further author information
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Zhiping Yug Department of Respiratory, Longshan Hospital of Traditional Chinese Medicine, Hunan, ChinaView further author information
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Yan Chena Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Shan Caia Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaView further author information
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Ping Chena Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China;b Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, China;c Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, ChinaCorrespondence[email protected]
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Pages 1317-1324 | Received 02 Nov 2022, Accepted 13 Mar 2023, Published online: 29 Mar 2023

Figures & data

Figure 1. Flow chart. COPD: Chronic Obstructive Pulmonary Disease; ICS: Inhaled Corticosteroid; LAMA: Long-Acting Muscarinic Antagonist; LABA: Long-Acting β2-Agonist.

Figure 1. Flow chart. COPD: Chronic Obstructive Pulmonary Disease; ICS: Inhaled Corticosteroid; LAMA: Long-Acting Muscarinic Antagonist; LABA: Long-Acting β2-Agonist.

Table 1. Baseline characteristics of the total less symptomatic COPD patients.

Table 2. Description of inhalation therapy.

Table 3. The clinical characteristics of different inhalation therapies on less symptomatic COPD patients.

Table 4. Exacerbation and mortality during one year of follow-up of different inhalation therapies on less symptomatic COPD patients.

Table 5. Exacerbation and mortality during one year of follow-up of different inhalation therapies on Groups A and C patients.

Supplemental material

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Data availability statement

All data of this study are available from the corresponding author Ping Chen for reasonable request.

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